Weizmann Institute of Science (WEIZ) is one of the leading multidisciplinary research institutions in the world. The Institute focuses on graduate and post-graduate studies in the sciences only, and is renowned for the seminal discoveries by its scientists in the biological and chemical sciences, as well in physics and mathematics. The Institute numbers more than 2,700 employees, including 1,000 scientists and scientific staff, 1,000 research students, 220 postdoctoral fellows and 400 administrative personnel. It has ~250 research groups headed by senior scientists and professors, and ~50 multidisciplinary research centres to promote joint projects in the various disciplines, including cancer research, brain research, nanotechnology, nuclear physics, computer technology, and solar and renewable energy research. The Weizmann Institute was the first in Israel to create an academically linked office for technology transfer and to initiate the creation of a thriving science-based industrial park, built near the Institute.
Prof. Edward Bayer
Professor. Department of Biological Chemistry. The Weizmann Institute of Science.
He co-discovered the multi-enzyme cellulosome concept and pioneered the development of designer cellulosomes for research and biotechnology. He authored over 350 articles and reviews, is editor of several biotechnology journals, is on the scientific advisory board of the DOE BioEnergy Science Center (BESC), and was elected to Fellowship of the American Academy of Microbiology and to the European Academy of Microbiology.
Interests: focus on structure-function consequences of protein-protein and protein-carbohydrate interactions, protein engineering, synthetic biology, nanobiotechnology, biomass degradation, genomics and bioinformatics of cellulosome-producing bacteria, and biomass-to-biofuels processing. The Bayer group has accumulated expertise in protein engineering and overproduction of recombinant enzymes. The group has developed novel approaches for the design and production of hybrid enzymes and chimaeric scaffoldins for self-assembly of designer cellulosomes and has experimentally proved their efficiency on lignocellulosic biomass.
Role in CellulosomePlus: The group will be mainly responsible for identifying, characterizing and selecting the various cellulosomal enzymes and structural components. The Bayer group will design and produce designer cellulosomal components, devise appropriate assays for their evaluation, and develop procedures for their facile self-assembly into mature multi-enzyme complexes. Within the consortium, the Bayer group will serve as lead for the following work packages: WP 2 and 8.